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Cosmelan 2 Depigmentation Cream

Cosmelan 2 is an extremely effective lightening cream designed to reduce hyperpigmentation. This depigmentation treatment helps to restore radiance and clarity by softly removing uneven pigmentation.

Benefits of Cosmelan 2 Depigmentation Cream:
  • An effective skin lightening cream
  • Reduces (or in some cases, eradicates) the appearance of dark spots
  • Creates an even skin tone and improves luminosity
  • Antioxidants protect against harmful free radicals
  • Suitable for use on all types of hyperpigmentation
  • Suitable for all skin types

Cosmelan 2 is an effective depigmentation cream that contains a blend of potent active ingredients that work together to lighten the skin on the face and other areas that have been exposed to the sun. With regular and continued use, the appearance of dark spots is dramatically improved and, in some cases, completely eradicated.

This hyperpigmentation treatment works by preventing the synthesis of melanin, inhibiting the production for so long that the skin continues its natural regeneration process; shedding away the top layers of the skin and taking the darker, pigmented areas with them.

Cosmelan 2 can be used on its own at home as part of your skincare regime, or as a maintenance cream following the in-clinic Cosmelan 1 treatment.

Cosmelan 2 contains a lower dosage of active ingredients than the Dermamelan cream.

Important information:

Please note: the use of Cosmelan 2, with its highly active ingredients, will cause skin redness and irritation in the initial stages and therefore the skin should be well prepped before use of this product begins. This helps to minimise possible adverse reactions and helps to optimise results. The use of Mesoestetic De-Pigmentation Skin Preparation Kit is required and should be used consistently for 15 days prior to treatment.

  • This product must be used with Mesoestetic products only: Mesoestetic Hydra Milk Cleanser, Mesoestetic Hydra-Vital Factor K,  Mesoestetic Melan Recovery, Mesoestetic Fast Skin Repair and Mesoestetic Ultimate W+ Range.
  • It is very important to wear a high SPF whilst using Cosmelan 2 Depigmentation Cream - we recommend Mesoestetic Moisturising Sun Protection SPF 50+, Mesoestetic Mesoprotech Melan SPF 130+ Pigment Control and Mesoestetic Mesoprotech Light Water Antiaging Veil

Instructions for use after in-clinic Cosmelan Treatment:

  • Apply Cosmelan 2 Depigmentation Cream directly over the entire face, three times a day (morning, midday and night), during the first four weeks (1st month).
  • From the fifth week (2nd and 3rd months), Cosmelan 2 Depigmentation Cream should be applied two times a day (morning and night), for eight weeks.
  • Cosmelan 2 Depigmentation Cream is used from week 13 (3rd month), continuing application once a day (at night), generally for a period of six months based on the obtained depigmentation results.
  • The use of a broad-spectrum sun protection is mandatory during Cosmelan 2 Depigmentation Cream usage. Not using sun protection reduces or invalidates the effectiveness of the product.

Instructions for use if you have NOT had in-clinic Cosmelan Treatment:

  • Apply Cosmelan 2 Depigmentation Cream directly over the entire face, once a day (at night), continually monitoring skin's progress.
  • When using Cosmelan 2 Depigmentation Cream, broad-spectrum SPF should be worn every day and re-applied throughout the day.
  • The use of a broad-spectrum sun protection is mandatory during Cosmelan 2 Depigmentation Cream usage. Not using sun protection reduces or invalidates the effectiveness of the product.

Mesoestetic Cosmelan 2 Depigmentation Cream is NOT suitable for use during pregnancy or breast-feeding.


Size: 30g